Autocamtide 2

CAS No. 129198-88-5

Autocamtide 2 ( Autocamtide II )

Catalog No. M29916 CAS No. 129198-88-5

Autocamtide-2 is a highly selective peptide substrate for calcium/calmodulin-dependent protein kinase II (CaMKII), which belongs to the CAMK Ser/Thr protein kinase family.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Autocamtide 2
  • Note
    Research use only, not for human use.
  • Brief Description
    Autocamtide-2 is a highly selective peptide substrate for calcium/calmodulin-dependent protein kinase II (CaMKII), which belongs to the CAMK Ser/Thr protein kinase family.
  • Description
    Autocamtide-2 is a highly selective peptide substrate for calcium/calmodulin-dependent protein kinase II (CaMKII), which belongs to the CAMK Ser/Thr protein kinase family.(In Vitro):The Ca/calmodulin dependent protein kinases (CaMKs) are multifunctional serine/threonine kinases whose activity are regulated through Ca2+ signaling. It is multifunctional best known for its critical role in learning and memory. Recent studies demonstrates that high levels of different isoform of CaMK, especially for CaMKII, expresses in several cancers such as lung, breast, prostate and colon cancer. CaMKII phosphorylates nearly 40 different proteins, including enzymes, ion channels, kinases, and transcription factors and plays a critical role in the regulation of proliferation, differentiation and survival of various cancer cells.
  • Synonyms
    Autocamtide II
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    129198-88-5
  • Formula Weight
    1527.8
  • Molecular Formula
    C65H118N22O20
  • Purity
    >98% (HPLC)
  • Solubility
    H2O : 20 mg/mL (13.09 mM; Need ultrasonic)
  • SMILES
    ——
  • Chemical Name

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

Wang YY, et al. The emerging role of CaMKII in cancer. Oncotarget. 2015 May 20;6(14):11725-34.
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